Express Scripts Offers New Value-Based Program for Migraine

Industry first SafeGuardRx Migraine Care Value Program Brings Affordability to Migraine Prevention and Treatment for Patients and Payers

ST. LOUIS, Oct. 17, 2018 - Migraine headaches are a painful reality for 39 million Americans. Severe migraine pain sends someone in the U.S. to an emergency room every 10 seconds, contributes to 113 million work days lost every year, costs employers $13 billion in lost productivity, and leads to billions of dollars spent in outpatient visits, emergency room visits and hospitalizations[i].

Recognizing a need to help patients and plans improve migraine management, Express Scripts (NASDAQ:ESRX) today announced its new SafeGuardRx SM Migraine Care ValueSM program will begin April 1, 2019.  This industry-first program combines a comprehensive clinical care program to help patients achieve better outcomes and experience fewer migraines, while helping plan sponsors more affordably cover new, preventive therapy for their members.

Moving to Preventive Care

"Right now, most patients take medication to make migraines go away. Our goal is to help frequent migraine sufferers prevent the migraine from coming on at all," said Harold Carter, PharmD, Senior Director, Product, Express Scripts. "Through the clinical care provided through our new Migraine Care Value program, Express Scripts specialist pharmacists in our Neuroscience Therapeutic Resource Center will identify patients using high amounts of acute migraine treatments, and work with them and their physician to move them to an appropriate preventive treatment."

Once on preventive therapy, these neuroscience specialist pharmacists will offer coaching for members to achieve optimal medication adherence, and to help members avoid migraine triggers.  For members using newer calcitonin gene-related peptide (CGRP) inhibitors, our pharmacists will coach them on how to use these injectable medications and overcome barriers to achieving optimal results.

Affordable Access to Breakthrough Treatments

Clinical evidence for recently approved CGRP inhibitors has shown these therapies are effective in reducing the frequency of migraine headaches in patients who experience four or more migraines per month. While drug makers have priced CRGP inhibitors in line with independent value-based assessments from organizations such as the Institute for Clinical and Economic Review (ICER), they are significantly more costly than previously available preventive migraine therapies and thus require conscientious management to ensure optimal patient outcomes.

Not all migraine suffers require CGRP-inhibitor therapy, but for those patients who meet the clinical guidelines for CGRP therapy, the Migraine Care Value program will prefer Aimovig™ (erenumab-aooe) and Emgality™ (galcanezumab-gnlm). As with any new-to-market medication, some patients will feel CGRP-inhibitors do not work for them. To help minimize plan sponsor exposure to the high cost of these therapies, Express Scripts is offering an early discontinuation reimbursement back to the plan sponsor when a patient discontinues therapy in the first 90 days.

"CGRP inhibitors can be life-changing for people with frequent migraines which is why it's critical that these drugs be made affordable to both patients and plan sponsors," said Carter. "With our SafeGuardRx solutions, we have pioneered an evidence-based approach that will now help migraine sufferers receive the best medication and specialized care to enable them to lead full and productive lives while reducing costs and wasteful spending for our clients."        

About Express Scripts

Express Scripts is a healthcare opportunity company. Empowered by our legacy as an industry innovator, we dare to imagine – and deliver – a better healthcare system with improved health outcomes and lower costs. From pharmacy and medical benefits management, to specialty pharmacy care and everything in between – we uncover opportunities to make healthcare work better.

Our home base is St. Louis, but our reach extends to millions of Americans across the nation. We stand alongside our clients and partners, collaborating to develop personalized solutions that make a meaningful difference in the lives of those we serve. We believe healthcare can do more. We are Champions For BetterSM.

Media Contacts